The Virus Strikes Twice

The Lancet has an article about a 25 year old man in Nevada who tested positive for COVID-19 in April and recovered but then at the end of May, he was infected again. He did not have any serious underlying conditions and there were no indications his immune system was compromised. But on May 28, he felt sick and on May 31 he got tested, and his test was positive. hThis time his symptoms were more severe.

We present, to our knowledge, the first North American case of reinfection with SARS-CoV-2. A 25-year-old man, who was a resident of Washoe County in the US state of Nevada, had laboratory-confirmed SARS-CoV-2 infection in April, 2020, followed by secondary infection within a period of around 6 weeks, in June, 2020. The second infection was symptomatically more severe than the first. Genomic analysis showed the two viral agents were genetically distinct. The patient's immune reaction in vitro was not assessed and, thus, conclusions cannot be made about the duration or degree of immunity.

The Lancet reports that at least 4 people have been reinfected. Does this man immunity Herd does not exist or individual immunity is not be a sure thing (unless you are a contestant on Survivor)? [More...]

Thus, previous exposure to SARS-CoV-2 does not necessarily translate to guaranteed total immunity. The implications of reinfections could be relevant for vaccine development and application. From a public health perspective, all individuals—whether previously diagnosed or not—must take identical precautions to prevent infection with SARS-CoV-2. Further work is needed to assess immune reactions in vitro after reinfection.

In other words, no one knows yet. Safest bet: Wear a mask, wash your hands, don't hang out in groups, avoid millenials who as a group don't seem to give a sh*t (in my neck of the woods anyway) and stay home as much as possible. If you can work from home, do so. If you're unemployed and need money, check out local resources and learn a new trade online. If you don't have to work, take an online class. Is it easy? No, but it's better than dying of COVID.

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    the assumed immunity, granted by virtue of having (5.00 / 2) (#1)
    by cpinva on Wed Oct 14, 2020 at 01:39:32 AM EST
    survived infection, hasn't actually been proved yet, it's mostly theoretical. as well, the original virus has probably evolved into a newer strain, which you have no anti-bodies to fight it off with. it's why we get a flu vaccine every year.

    basically, at this point, as you note, we're kind of screwed.

    The key sentence, which explains a lot, is: (5.00 / 3) (#4)
    by scribe on Thu Oct 15, 2020 at 09:46:53 AM EST
    " Genomic analysis showed the two viral agents were genetically distinct."

    In other words, he had a case of Virus #1, got over it, and then got a case of Virus #2 a month or so later.

    Going back at least 4 or 5 months, there have been a number of reports in various media (mostly in Europe) to the effect that the coronavirus had either mutated or that there were a couple closely related strains running around.

    So, just like we all get colds repeatedly because the common cold virus is not one but rather many different, closely-related viruses, the same seems true with Cousin Corona.

    It's hard to sort through the reports and articles.  There was one a week or two ago which tried to correlate or drew a connection between (on the one hand) how severe a patient's symptoms turn out to (on the other) how much Neanderthal DNA that person has. (Gene studies and such suggest pretty uniformly that most of us seem to have some.  It's said NFL linebackers ... no, just kidding about the linebackers.)

    Right now, a lot of what's going on at least in the public, non-scientific press, is drawing connections like we do constellations in the sky from a whole bunch of points of light.  

    Wash your hands.

    Please, say it ain't so, Joe (5.00 / 2) (#12)
    by Peter G on Thu Oct 15, 2020 at 07:41:39 PM EST
    "I will pick up the phone and a call a fair-minded Republican and ask what we can get done, how to work it out." Sadly familiar, and I mean "sadly" literally.

    He is pitiful. But I'm still glad that I voted (5.00 / 2) (#15)
    by Peter G on Thu Oct 15, 2020 at 07:50:29 PM EST
    today for Kamala Harris to become President in a few years. Unfortunately, that vote came packaged, but hey, the world is complicated. Meanwhile, it will obviously be a vast improvement.

    I got my ballot today!! (5.00 / 1) (#19)
    by Chuck0 on Thu Oct 15, 2020 at 07:59:57 PM EST
    Finally. Will deliver it in person tomorrow.

    CHECK FIRST (none / 0) (#29)
    by jmacWA on Fri Oct 16, 2020 at 04:56:28 AM EST
    Chuck, our local ballot box at the town hall doesn't open until next Monday.  If you have a long drive you might want to make sure they are open.

    Six minutes into downtown is my drive (none / 0) (#44)
    by Chuck0 on Fri Oct 16, 2020 at 10:22:22 AM EST
    There is a Dropbox in the lobby of the county bldg. I just hope the handicap spot is available on the street out front.

    Apparently something like half the country (none / 0) (#18)
    by CaptHowdy on Thu Oct 15, 2020 at 07:59:30 PM EST
    thinks democrats will "25th amendment" within weeks of the inauguration.

    So there's that hope, I suppose.


    What (5.00 / 2) (#41)
    by Zorba on Fri Oct 16, 2020 at 10:09:37 AM EST
    fair-minded Republicans?  I can't name one.

    Did you check out the ... (5.00 / 1) (#45)
    by Erehwon on Fri Oct 16, 2020 at 10:31:24 AM EST

    Better than the other one (none / 0) (#13)
    by CaptHowdy on Thu Oct 15, 2020 at 07:46:16 PM EST
    Now this is Dingbat who is leaning slightly to Biden...

    Thank you, Mr President you have such a wonderful smile.

    Thank you thank you

    You are SO handsome when you smile.  


    I don't remember what Dingbats question was.


    It (5.00 / 1) (#16)
    by FlJoe on Thu Oct 15, 2020 at 07:55:04 PM EST
    was about immigration, from a lily white person...par for the course I suppose.

    And I like the staging with the lady in the frame with tRump constantly nodding in agreement with him.


    If you expect anything (none / 0) (#21)
    by MO Blue on Thu Oct 15, 2020 at 08:03:49 PM EST
    else from Biden, I think you will be sadly disappointed. While the Republicans are publicly plotting to sabotage a Biden administration, Biden is thinking of all the ways he can roll over and pass Republican legislation so he can claim he is bipartisan. I predict the deficit will suddenly become of utmost importance in Biden's first term.  

    You know (5.00 / 2) (#22)
    by CaptHowdy on Thu Oct 15, 2020 at 08:12:38 PM EST
    I was thinking, if there is a blue wave the worst outcome might be that he begins to imagine it had anything to do with him and his bipartisan BS.

    If he starts trying to pi$$ away an actual mandate.....see 25th amendment comment above.


    Don't think the Dems will do that (5.00 / 3) (#24)
    by MO Blue on Thu Oct 15, 2020 at 08:27:26 PM EST
    It will be better than Trump. With old politicians like Biden and Feinstein, I doubt we will get the programs we need to turn this country around.

    When Joe Biden (none / 0) (#25)
    by KeysDan on Thu Oct 15, 2020 at 09:22:15 PM EST
    defeats Trump he will have made his most significant contribution to the country.  He could retire shorty thereafter and enjoy a legacy of saving the country.  The state of the Union is so fraught, A peaceful reclamation of democracy and the rule of law will put him up there with Abe Lincoln. If this statement seems to be hyperbole, we just need to contemplate what would remain of the nation with four more years of Trump, and Ivanka following him.

    However, I have a moderate to high level of confidence that a Biden/Harris Administration will be progressive, if for no other reason that restoring Trump damage will necessitate substantive governmental action.  And, the prospects are good for filling Cabinet and other key posts with well-qualified appointments.  And, then there is the re-balancing of the SC.

    Many voters are still living with the fantasy of bipartisanship and can't we just all get along.  Biden's speaking to this is a worry, but, hopefully, it is speaking to an ideal while recognizing the reality.  


    I would prefer that you are right (5.00 / 3) (#26)
    by MO Blue on Thu Oct 15, 2020 at 10:22:32 PM EST
    Personally, I am of the opinion that he is a true believer in bipartisanship and retaining the old rules of the Senate.

    I would be pleasantly surprised if Biden got behind eliminating the filibuster and re-balancing the SC.


    Definitely (5.00 / 1) (#27)
    by Ga6thDem on Fri Oct 16, 2020 at 03:31:51 AM EST
    a legitimate worry. I now believe Obama may have picked him for VP because he is an ideological soulmate. If he still is invested in this fantasy 1970's bipartisanship after 8 years of Obama I just have no words.

    Biden's answer on (none / 0) (#46)
    by CaptHowdy on Fri Oct 16, 2020 at 10:57:26 AM EST
    The courts last night was much better than the previous "court packing" one.

    It was a pretty good answer.


    Yes, it was (5.00 / 1) (#49)
    by KeysDan on Fri Oct 16, 2020 at 01:16:28 PM EST
    encouraging.  All the more ire for Senator Feinstein's kissy face and grand bow to Lindseybelle.

     Senator Feinstein, the ranking minority member of Judiciary, gave legitimacy to the rushed and inappropriate hearings making campaigns for Court reform more difficult.  We can look forward to the Republican TV ads.


    Why, og why, did she do this? (none / 0) (#50)
    by oculus on Fri Oct 16, 2020 at 03:17:03 PM EST
    Rachel just played that bit (none / 0) (#23)
    by CaptHowdy on Thu Oct 15, 2020 at 08:18:04 PM EST
    The look on her face after was great.  

    Just MAYBE (none / 0) (#30)
    by jmacWA on Fri Oct 16, 2020 at 05:01:00 AM EST
    Trump is right and he is senile.  

    He thinks he is dealing with an honorable group of people.  IMO there is no Elected or Selected Republican with any honor anymore.  Every single one in every branch of government (including Judicial) at every level needs to go.  They party has been turned into a cult by using the media and their money to dupe the American electorate.

    IF Biden puts one Republican in his cabinet he is a fool and has not been paying attention for the last 40+ years.  Regan introduced the GOP as cult, Gingrich solidified it with his drive for a solid non-partisan voting block, and Trump has cemented it into place.  The GOP needs to be rebuilt from the ground up... and really we just need a NEW second party.


    Caroline Giuliani: (5.00 / 1) (#47)
    by desertswine on Fri Oct 16, 2020 at 11:03:52 AM EST
    "I may not be able to change my father's mind, but together, we can vote this toxic administration out of office."

    "If being the daughter of a polarizing mayor who became the president's personal bulldog has taught me anything, it is that corruption starts with 'yes-men' and women, the cronies who create an echo chamber of lies and subservience to maintain their proximity to power," Caroline Giuliani wrote. "We've seen this ad nauseam with Trump and his cadre of high-level sycophants (the ones who weren't convicted, anyway)."

    I had planned to go to (none / 0) (#2)
    by ragebot on Wed Oct 14, 2020 at 12:27:03 PM EST
    Germany last January to buy a boat to cruise the canals in Europe during the hurricane season in Florida.  I had located what seemed to be a good deal there and had even contacted a friend in Norway to check it out before I left.  Of course COVID-19 put an end to that but it did result in my staying in contact with several friends in the EU about how COVID-19 limited travel in the EU.  

    Bottom line is we are still to early in our research of COVID-19 to say how to best deal with it.

    We had planned (none / 0) (#43)
    by Zorba on Fri Oct 16, 2020 at 10:17:55 AM EST
    To take a canal cruise in Europe for our 50th wedding anniversary this year.  
    Alas, that could not happen.

    Savannah Guthrie (none / 0) (#5)
    by CaptHowdy on Thu Oct 15, 2020 at 06:55:27 PM EST
    Is pathetic

    She just let Trump open with the lie about 85% of mask wearers get it.

    I'm watching Biden. (5.00 / 1) (#7)
    by desertswine on Thu Oct 15, 2020 at 07:20:08 PM EST
    I can't say that he's mesmerizing, but he's not crazy.

    I have his town hall (5.00 / 1) (#10)
    by MO Blue on Thu Oct 15, 2020 at 07:26:03 PM EST
    Streaming on three devices to help his ratings. Actually, have them on mute now. IMO, he often continues to talk after he has made his point. He would be more effective, sharper  (reduce boredom ratio) if he quit once his point was made.

    I'm technically watching both (none / 0) (#11)
    by CaptHowdy on Thu Oct 15, 2020 at 07:32:32 PM EST
    Picture in picture

    I have no interest (none / 0) (#17)
    by MO Blue on Thu Oct 15, 2020 at 07:57:03 PM EST
    In watching the orange raccoon lie and talk nonsense. I will get a brief (key word) run down of his performance after he is through.

    Not worth it (none / 0) (#20)
    by CaptHowdy on Thu Oct 15, 2020 at 08:03:28 PM EST
    It was a farce and complete waste of time.  

    They just released the ratings (5.00 / 2) (#48)
    by MO Blue on Fri Oct 16, 2020 at 12:49:51 PM EST
    for the dueling town halls.

    No bragging rites for the orange one. Biden had more viewers on 1 station than Trump could garner on 3.  

    Hurray for the good guys.


    Back and forth (none / 0) (#8)
    by CaptHowdy on Thu Oct 15, 2020 at 07:23:30 PM EST
    It is quite a contrast. This NBC thing is a disgrace.  A pathetic disgrace.  NBC is proving every thing everyone said about them.  This is Apprentice level bad.  Trump of course looks insane.  

    I can't wait to see if MSNBCs self serving (none / 0) (#9)
    by CaptHowdy on Thu Oct 15, 2020 at 07:24:51 PM EST
    Bobble heads admit how bad this is.

    Rachel (none / 0) (#14)
    by CaptHowdy on Thu Oct 15, 2020 at 07:47:25 PM EST
    Well, that happened.

    We DID NOT produce that event.


    Pathetic (none / 0) (#6)
    by CaptHowdy on Thu Oct 15, 2020 at 06:57:10 PM EST
    Probably why he agreed to it.  Knowing he could roll right over her.  And he is.

    Ironically (none / 0) (#28)
    by Ga6thDem on Fri Oct 16, 2020 at 03:32:46 AM EST
    the Trumpers are crying all over twitter that Guthrie was mean to Trump. Since I didn't watch I can't comment.

    From (none / 0) (#31)
    by FlJoe on Fri Oct 16, 2020 at 05:28:45 AM EST
    the parts I watched she did a decent job (it's hard to question/debate with a mad man). This definitely was a highlight
    On spreading the conspiracy that Obama had SEAL Team 6 killed.

    TRUMP: "That was a retweet! People can decide for themselves!"

    GUTHRIE: "You're the president, you're not someone's crazy uncle."

    Mary Trump (5.00 / 3) (#42)
    by Zorba on Fri Oct 16, 2020 at 10:15:57 AM EST
    Begs to differ.

    It was the only "highlight" (none / 0) (#32)
    by CaptHowdy on Fri Oct 16, 2020 at 06:51:14 AM EST
    It was a Today Show line.  

    And first he absolutely IS someone's crazy uncle.  I disagree.  It's not that hard to say, that a lie.   Or even that not true.  She never even tried


    If asking him questions (none / 0) (#33)
    by CaptHowdy on Fri Oct 16, 2020 at 06:52:55 AM EST
    That require him to lie repeatedly and never challenging him once is being mean.  I guess they might think it was because that never happens to him.

    He repeated the "85%" lie about masks (none / 0) (#34)
    by CaptHowdy on Fri Oct 16, 2020 at 06:59:42 AM EST
    twice.  Crickets. .  Tho actually one time she actually agreed that Fauci said don't wear masks.  Without bothering to explain he said it very early because they were worried about the supply for frontline workers so they were afraid to start a toilet paper like run in masks.

    She was pathetic


    I (5.00 / 1) (#35)
    by FlJoe on Fri Oct 16, 2020 at 07:21:01 AM EST
    disagree, she did pushback on the mask thing, at least the time I saw. It wasn't her strongest moment though.

    She positively hounded him about his covid testing timeline, Q-Anon and his massive debt. Of course she couldn't get the truth out of him(nobody could) but she did manage to get some damaging half truths out of him.


    She got him to lie for an hour (none / 0) (#36)
    by CaptHowdy on Fri Oct 16, 2020 at 07:39:58 AM EST
    Not much of an accomplishment.

    Of (none / 0) (#37)
    by FlJoe on Fri Oct 16, 2020 at 07:51:41 AM EST
    course he lied for an hour, no one expected otherwise. I think she drilled down enough to get tRump to dance around and qualify his lies to a greater degree than previous moderators.

    On the covid testing she got him to admit he wasn't tested everyday and that he was "maybe" tested the day of the debate.


    We will agree (none / 0) (#38)
    by CaptHowdy on Fri Oct 16, 2020 at 08:49:40 AM EST
    To disagree.

    I was thinking that Trumps strategy of getting his yahoos to flood the polls on Election Day maskless and defiant could really hit a snag if the current upturn turns into a massive second wave.

    It looks possibly perfectly timed to be peaking on Nov 3rd.

    As they are saying more than 150 million votes may be cast early.  


    Run this graph out (none / 0) (#39)
    by CaptHowdy on Fri Oct 16, 2020 at 08:52:24 AM EST
    One more month



    Just heard a doc say (none / 0) (#40)
    by CaptHowdy on Fri Oct 16, 2020 at 09:05:26 AM EST
    By Election Day there will be 70,000 dead per day.  Or more.

    Another lie (none / 0) (#51)
    by Yman on Fri Oct 30, 2020 at 08:29:37 AM EST
    You really need to stop spreading lies about the virus.

    that comment was deleted (none / 0) (#52)
    by Jeralyn on Mon Nov 02, 2020 at 12:59:04 PM EST
    for spreading false information about masks. Thanks for pointing it out